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IOEBA'S Puppy Vaccinations - Why, When and How |
GLOSSARY OF TERMS
Antibodies:
Proteins made by the immune system that attach to disease agents to signal
the other parts of the immune system to negate and destroy it.
Vaccination:
Altered disease agents that do not cause disease but
do allow the body to develop protective antibodies to the disease agent
conferring immunity to the disease.
Infectious Canine Hepatitis aka Adenovirus:
Is a viral disease spread by contact with
infected animals, their feces, urine, or saliva. It affects the liver,
kidneys, and cells lining the blood vessels.
Symptoms include high fever,
thirst, inflammation of nose or mouth, diarrhea, abdominal pain and
tenderness, liver damage, loss of appetite, hemorrhage, and depression.
Vaccination provides
excellent immunity. Initial vaccinations are given as
a series beginning as
early as 6-8 weeks, followed by annual booster shots. The vaccine for canine
hepatitis is usually combined with one for distemper.
Bordetella: (Kennel Cough) in dogs is similar to the common cold in humans.
Although this disease is rarely fatal, it can lead to other diseases such as
pneumonia which can shorten your dog's life. Kennel cough occurs more
commonly in puppies and young adult dogs, and in dogs that have recently
been in shelters or exposed to many other dogs. Since kennel cough is
caused by an airborne virus, normal cleaning and surface disinfecting cannot
eliminate the cause. Kennel Cough can occur with Distemper,
Adenovirus Type Two, Parainfluenza and other respiratory infections.
Antibiotics can prevent or cure a secondary infection. Cough suppressants
can be used to control the cough. To help prevent pneumonia or other
diseases, dogs with Kennel Cough should be kept in a warn environment.
Keep infected dogs away from other dogs to prevent further transmission of
any disease. Like the common cold, Kennel Cough cannot be cured but it has
to run its course.
Symptoms include harsh dry
(honking) cough that is often followed by gagging and coughing up foamy
mucous, with nasal discharge of clear turning to milky white, and then to
green. Most infected dogs do NOT have a fever and otherwise the dog
appears alert and generally healthy.
Vaccination
is minimally effective. There are some 40 plus strains of Kennel
Cough and the vaccination provides protection against approximately 12.
However, if your dog is shown, to be kenneled, or is to be around a number
of other dogs it is wise to have your dog vaccinated. The intranasal
vaccine is pretty fast acting, providing some protection in as little as 5
days. The injectable version of the vaccine may provide longer immunity.
Some vets use both to get maximum protection. Please do not assume
that any cough is Kennel Cough. If your dog has a fever, is less active than
normal, has a decreased appetite, has a discharge from the eyes and nose,
has difficulty breathing or is older than three years, the above-named
symptoms are signs of a more serious problem and you need to see a
veterinarian as soon as possible
Corona virus:
Takes only 24 to 36 hours to incubate. This virus spreads rapidly through
exposed dogs. Corona virus is an intestinal infection resulting in
diarrhea, vomiting and depression. Corona virus can affect a high
percentage of dogs, and can cause death in young puppies. Corona virus
infection can also make an animal more susceptible to other intestinal
diseases.
Symptoms include vomiting and
diarrhea (sometimes bloody) and this leads to dehydration. Unlike
Parvo, the mortality rate is low and affected dogs generally feel better in
a few days, though fluid treatment may be needed.
Vaccination is the only effective
control. Initial vaccinations are given as a series beginning as early
as 6 weeks, followed by annual boosters. Corona virus vaccinations are
usually given in combination with vaccines for other diseases.
Distemper: Is a highly contagious and often fatal virus that affects a dog's
respiratory, gastrointestinal, and nervous systems. It can be spread
as an airborne infection or through contact with an infected animal, its
feces, or its urine. Because a puppy's natural maternal immunity may
wear off before he is vaccinated, reduce risk of exposure by limiting
contact with unfamiliar dogs until vaccination series is complete.
Symptoms include coughing, sneezing,
nose and eye discharges, fever, depression, vomiting, diarrhea, lack of
appetite, and seizures.
Vaccination is the only effective
control. Initial vaccinations are given as a series beginning as early
as 6 weeks, followed by annual boosters. Distemper vaccinations are
usually given in combination with vaccines for other diseases.
Leptospira:
is an extremely contagious bacterial disease that spreads through contact
with nasal secretions, urine, or saliva of infected animals. Early
signs are not apparent, so infection can go undetected. Recovered
animals can continue spreading the disease, which can also affect humans.
Symptoms may include inflamed
kidneys, fever, vomiting, diarrhea, loss of appetite, and listlessness.
Liver damage can also occur. Note that early signs of the disease may
not be readily apparent.
Vaccination is available for
Leptospirosis. Initial vaccinations are given as a series beginning as
early as 6 weeks, followed by annual boosters. Leptospirosis
vaccinations are usually combined with vaccinations for distemper and
hepatitis (DHL).
Lyme Disease:
A disease complex caused by a spirochete called Borrelia burgdorferi
that has acute effects of flu-like symptoms of fever, malaise, impedance
and more chronic effects of arthritis, muscular disease, and neurological
disease. It is highly responsive to treatment if caught early.
As the disease progresses it becomes less and less responsive. It is
transmitted by ticks, and, thus, tick prevention is considered the optimum
prevention program. In the US the only area of significant risk at
this time is considered to be the Northeastern states. This will
probably change as more information is collected.
Parainfluenza: Often acting in conjunction with the Bordetella (technically known as
Tracheobronchitis), this virus-bacteria combination causes kennel cough
syndrome, which can spread rapidly through a group of dogs. This
respiratory disease may last several weeks and is highly
contagious but can get better on its own, unless a secondary bacterial
infection occurs which may produce fever and a longer recovery. Incubation
period is between 5-10 days.
Symptoms include harsh dry (honking)
cough that is often followed by gagging and coughing up foamy mucous,
otherwise the dog appears alert and generally healthy.
Vaccination is given as a series
beginning as early as 6-8 weeks, followed by annual booster shots. The
vaccine for Canine Parainfluenza is usually
combined with one for
Parvovirus.
Parvovirus:
Is a highly contagious viral disease which can
affect dogs of all ages, but is especially deadly in puppies. Spread
through the feces of infected dogs, this hardy virus can survive for months
within feces at less than 20 degrees. It is easily carried on shoes,
clothing, and by flies. The incubation period is generally 4 to 7 days
but may vary from 2 to 4 days. Parvovirus attacks rapidly growing
cells, so it especially likes the bone marrow and the cells lining the
intestine. Parvovirus infects the cells that line the intestinal tract causing their
death and sloughing. As a result, profuse, bloody diarrhea occurs.
Death commonly occurs due to fluid, electrolyte, and blood loss and due to
secondary systemic bacterial infections via the damaged gut. Puppies
are the most susceptible to Parvovirus infections.
Symptoms include depression, lack of
appetite, vomiting and bloody diarrhea. Suppression of the immune
system leaves the dog wide open to secondary bacterial infections.
Death usually occurs due to insurmountable dehydration, and a large
percentage of infected dogs may die, despite excellent medical care.
Vaccination is the only effective
control. Initial vaccinations are given as a series beginning as early as 6
weeks followed by annual boosters. Parvovirus vaccinations are usually
given in combination with vaccines for other diseases.
Rabies:
A virus that invades via bite wounds into the muscle,
up the nerves, to finally reside in the brain. As a result of its
residence, neurological
damage occurs and dogs exhibit a wide range of neurologic signs -- rage,
inability to swallow, stupor, increased salivation, and
staggering.
Rabies is spread via the saliva and is infective to any mammal. Rabies
is 100% fatal once it reaches the brain in any species.
Why do I need to vaccinate my puppy?
The immune system of the dog is designed to produce
antibodies, a type of
protein, to disease agents (such as bacteria, viruses, protozoa, fungi, etc).
These antibodies protect the body from infection and disease by binding to the
disease agent and marking it for destruction by other parts of the immune system
like killer cells, phagocytic cells, and the complement system. Thus,
antibodies are the body's protection against
disease.
When do antibodies form?
Antibodies
form ONLY after an initial exposure to a disease agent.
During this initial exposure the dog has no protection from the disease agent,
and, therefore, the disease must run its course. In addition, antibodies
are very type specific -- antibodies to a type specific virus such as the Parvo
virus do not protect the dog from any other disease agent except Parvo.
Thus, a dog must experience each disease before it will become protected against
that disease. For some diseases this is not significant because the
disease is mild and has little effect upon the dog. Other diseases,
however, are more significant and can lead to serious sickness and even death.
This is how Mother Nature has designed the immune system to work.
The drawback to her plan is that the dog has to survive the initial disease
exposure in order to develop protective antibodies, ie become immune, to the
disease. As mentioned earlier with many diseases this is not a significant
problem because they are mild and cause little lasting effects. There are,
however, life-threatening diseases that the dog may not survive the initial
exposure to. Human ingenuity came along and said what if we could expose
dogs to the disease agents of these serious illnesses in such as way as to allow
them to develop protective antibodies but not develop disease. And so the
vaccine was invented.
All a vaccine is
is an altered form of a disease agent such as Parvo that can be given to a dog
(or other species) in order to stimulate the dog's immune system to produce
protective antibodies without the concurrent development of disease.
With the introduction of vaccines, many devastating canine diseases like
Rabies, Canine Distemper, Infectious Canine Hepatitis, and Parvo were rapidly
reduced in occurrences and canine mortality rates plummeted. We today do
not fully appreciate the impact that these diseases had on canine populations
pre-vaccination and can be without the puppy hood vaccine regime. An
unvaccinated dog has
absolutely NO
protection against any of these disease. Do
not be fooled into thinking that these diseases have been eradicated and are no
longer a significant health threat. These diseases are still maintained at
significant levels in wildlife reservoir hosts (raccoons, foxes, coyotes) and in
feral dog populations. And as more people choose to never vaccinate their
dogs these diseases will begin to increase among the domestic dog population as
well. Thus, the risk of disease exposure is present and is present at a
very significant level. Vaccination is our way of using Mother Nature's
brilliant system of disease protection to maximum benefit -- protection without
the need for initial disease.
Why do puppies need so many
vaccines? Isn't one enough?
Puppies like all young mammals receive antibodies from their mother to
passively protect them from disease until they are old enough for their immune
systems to produce their own antibodies. They receive these antibodies
during the first 24-36 hours of life in the first milk, or colostrum.
This maternal antibody transfer is why it is so important that puppies nurse as
much as possible during the first day of life.
How long these antibodies last is highly individual and varies considerably from
puppy to puppy even among littermates. The duration of maternal antibodies
is a function of how much colostrum they received, how concentrated the
antibodies were in the colostrum (ie, how high the mother's antibody levels
were), how fast the puppy's metabolism breaks down the antibodies (like any
protein they are degraded over time), and the amount of exposure that the puppy
has to disease agents.
Herein lies the difficulty of vaccinating a puppy. If the maternal
antibodies are at too high of a level then the vaccine will be negated and
stimulate no response on the part of the puppy's immune system. But if the
maternal antibodies drop too low then puppy is at risk for developing disease.
When the maternal antibodies are high enough to protect from disease but low
enough to allow the vaccine to stimulate a response from the puppy's immune
system is the window of optimum vaccination.
When does this window happen? Anywhere from 3 weeks to 24 weeks with
average being 6 to 15 weeks and at different times for different diseases.
Therefore, we are left with two options:
(1)
wait until puppy is 6 months old to vaccinate and leave puppy at great risk for
developing life-threatening illness like Distemper or Parvo or
(2) vaccinate puppies at
regular intervals beginning at 6 to 9 weeks so that we "catch" the puppy during
its window while at the same time minimizing the time that the puppy is at risk
for developing disease. The latter option maximizes protection while
minimizing risk and is, consequentially, the safest and most appropriate method
of vaccinating puppies. This is the rationale behind the need for series
of repeated puppy vaccinations beginning at 6 to 9 weeks and continuing every 2
weeks until the puppy is 4 to 6 months old.
It is
absolutely critical to vaccinate puppies
if we expect to continue to see reduced incidence of fatal canine diseases like
Distemper and Infectious Canine Hepatitis. Parvo already claims thousands
of puppies a year and will claim thousands more if puppies are not vaccinated
properly. These diseases are out there and an
unvaccinated puppy has absolutely NO protection
from them; failure to vaccinate a puppy puts it in a great deal of unnecessary
danger. Once puppy vaccinations have produced antibodies to disease
agents, frequency of vaccine boosters is something to be discussed with your
veterinarian. Ample scientific data suggests that current canine vaccines
give protection in most dogs for 2 years. Whether you opt to vaccinate
yearly, every other year, or check antibody levels via titers and only vaccinate
as needed is a matter of personal preference in adult dogs. Regardless of
your decision regarding vaccination of adult dogs, every puppy needs to be
vaccinated and every adult dog needs an annual physical exam to detect any
health problem as early as possible. And also be sure to consult local law
before deciding upon frequency of Rabies vaccination most places allow 3 year
vaccines but some high risk areas have counties that require yearly Rabies
vaccine still.
Puppy Vaccination Schedule
Beginning at 6 weeks of age:
One Measles, Distemper , Parvovirus, Parainfluenza, and Adenovirus vaccine.
This is usually all in one injection called a 5 in 1 or a 5 way vaccine.
Two weeks later -- 8 weeks of age: One Distemper, Parvovirus, Parainfluenza, Adenovirus, Leptospira 1 and 2
vaccine +/- a Coronavirus vaccine. This is usually all in one injection called
a 7 in 1 or a 7 way vaccine.
Two weeks later -- 10 weeks of age:
One Distemper, Parvovirus, Parainfluenza, Adenovirus, Leptospira 1 and 2
vaccine +/- a Coronavirus vaccine. This is usually all in one injection called
a 7 in 1 or a 7 way vaccine.
Two weeks later -- 12 weeks of age:
One Distemper, Parvovirus, Parainfluenza, Adenovirus, Leptospira 1 and 2
vaccine +/- a Coronavirus vaccine. This is usually all in one injection
called a 7 in 1 or a 7 way vaccine.
At 13 or 14 weeks of age:
A
Rabies vaccine. If to be boarded a Bordetella vaccine. If in an
area of high risk (ie NE USA) the first Lyme vaccine.
It is recommended for puppies of American Pit Bull Terriers, and other
Bull breeds to have a Parvovirus booster vaccine at 5 to 6 months of age
since, for some reason, these breeds seem more susceptible to parvovirus
infection whether from a innate susceptibility or because of such high
maternal antibody levels that the vaccine cannot confer protective antibodies
at times until this age.
Some things to note:
- The new parvovirus vaccines claim full protection at 12 weeks of age.
If your veterinarian is using one of these products you can, theoretically,
stop parvovirus vaccination after the twelve week vaccination.
- Lyme, Corona virus, and Bordetella vaccines are all considered optional
vaccines. The decision to vaccinate for these diseases needs to be made
after assessing risk of disease for your pet and what activity your pet plans
to engage in. For example, a pet to be boarded needs a Bordetella
vaccine. Those not to be boarded within 6 months have no need for it.
Discuss with your veterinarian the appropriateness of these vaccines for your
pet.
- An unvaccinated puppy greater than 3 months of age needs two
vaccinations 2-3 weeks apart for Distemper, Parainfluenza, Parvovirus,
Adenovirus, Leptospira 1 & 2, +/- Corona virus and one Rabies vaccination.
Lyme and Bordetella are optional.
- This vaccination regime holds for puppies in the United States and
Canada. Dogs in other countries have different disease risks so my
advice is to consult your veterinarian for appropriate disease prevention for
your area.
FINALLY LET ME REITERATE THAT YOUR PUPPY WILL BE EXPOSED
TO DISEASE NO MATTER HOW CAREFULLY YOU ISOLATE OR SEGREGATE IT.
THE QUESTION IS WILL THE PUP BE PROTECTED VIA VACCINATIONS OR WILL IT BE
VENERABLE AND SUSCEPTIBLE TO DEVELOPING LIFE-THREATENING DISEASES BECAUSE OF YOUR CHOICE NOT
TO VACCINATE???
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